CNS Mapping and Knowledgebase
CNS
The L&MARK NPGIS Initiative (Neuro Proteomics & Genomics Information System) provides a component based solution supporting CNS discovery processes.
The 2D/3D rat brain map ensures a quick and reliable identification of brain region of interest. Furthermore, the GIS (Geographical Information System)
approach allows using the brain map as common identification system considering topological features of the brain. A comprehensive knowledge base is
implemented "behind" the brain map. This way all relevant information can be collected and assigned to the particular brain regions and to each other.
The database can be enhanced by other new entities (e.g. neuropeptides) and relations tailored for CNS discovery project purposes.
The knowledge base can integrate fMRI, PET and output of other brain mapping technologies. Comparative evaluation of microarrays.
The main benefits of the GIS based approach of mapping the brain are:
- Quick and easy query of morphological information
- Common identification system for all relevant data
- Management of huge amount of genomics and proteomics data
- Common evaluation of brain mapping information, genomics and proteomics data considering morphological and topological features of the brain.
- Simulation of brain processes
- Considering protein-protein interaction network
- Comprehensive prediction algorithms for target validation
- Comprehensive toolset supporting biostatistics evaluation
- 3D visualization of evaluation results.
Click on the picture.
Brain map
Using this brain map our customers will be able to integrate, manage and evaluate all research related information coming from different
sources in a common knowledge base very easily. Just like a map for scientists.
Click here to try BrainMap (Rat)
CNS evaluation tools
There are several evaluation tools implemented in the system. You can use parametric and non-parametric biostatistics, 3D visualization of
database query result, report generation tools, business graphic generation, correlation analysis and a lot more. This part of services will
be continuously developed according to new customer requirements.
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